Available tissue

Sample storage conditions

formalin-fixed and paraffin embedded (FFPE)
frozen
fresh samples, provided in media or fixatives according to the researcher's protocol (on request)
formalin-fixed, not paraffin embedded (on request)

Sample type

Cerebellum	Olfactory bulb
Hypothalamus	Normal appearing white matter
Hippocampus	MS lesions (active, inactive)
Locus coeruleus	MS lesions dissected on MRI guidance
Substantia nigra	DNA
Medulla oblongata	Cerebrospinal fluid
Striatum	Plasma
Spinal cord	Microglial cells
Dorsal root ganglia	Eyes (See eye donation)
Cortex (Frontal, Temporal, Parietal, Occipital)	Human induced pluripotent stem cells (iPSC’s) from the NBB-Psy donor program.

Requests for specific brain areas are taken into account when performing autopsies. Please note that for MS different brain areas are specified, because MS brains are dissected using a specific protocol.

Anonymized Donor information

The tissue is accompanied by anonymized donor information, including the neuropathological report and an extensive summary of the donor’s medical history. The tissue can be matched for ante-mortem parameters (e.g. age, sex, time and season of death, agonal state, pH, APO-E genotype) and post-mortem parameters (post-mortem delay, freezing or fixation procedure, storage time).