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Application Form Netherlands Brain Bank







Suggested precautions for handling human brain tissue
Postmortem human tissue and fluids may contain highly infectious agents and have potential risks of diseases that are highly communicable to other humans. All such tissue and fluids should be treated as being a risk for such transmission and handled carefully. Studies have shown several extremely hazardous agents (viruses, bacteria, prions) to be very stable. The Creutzfeldt-Jakob (CJD) prions, for example, remain transmissible even after 30 years of tissue fixation. The agent has also been shown to withstand conventional autoclaving. Although relatively rare, there is no quick screening method for such agents, and adequate caution must be exercised.

We recommend to handle non-fixed tissue under a biohazard hood with all personnel taking special care. Any waste material should be treated as a biohazard and discarded according to your institution's policy for handling such material, i.e. auto¬claving.

Requirements for tissue recipients
The NBB only supplies tissue, CSF and plasma (Material) that has been obtained on the basis of informed consent of the brain donor. Informed consent restricts the use of the Material to scientific research purposes only. The Material shall only be supplied under the conditions stated in a Material Transfer Agreement (MTA), that needs to be signed by the person who is granted the power of representation within your organization. The MTA states the rights and obligations of the Provider as wel as the Recipient with regard to the Material and its use.

Contact information
In case you need further information or have questions concerning the application form or availability of tissue, please don't hesitate to contact us or look at our website (www.brainbank.nl). Please return the completed application form to eNBB@nin.knaw.nl.